Table 3

Most read topics among Global Health Delivery UpToDate (GHD-UTD) users by continent

	Africa		Asia		North America		South America
Rank	Term	Frequency	Term	Frequency	Term	Frequency	Term	Frequency
1	Clinical manifestations of malaria	404	Overview of the management of hepatitis B and case examples	154	Epidemiology, microbiology, clinical manifestations and diagnosis of typhoid fever	161	Pre-eclampsia: clinical features and diagnosis	57
2	Treatment of severe falciparum malaria	394	Overview of hypertension in adults	147	Metronidazole (systemic): drug information	156	Epidemiology, pathogenesis and clinical manifestations of Ebola and Marburg virus disease	41
3	Initial assessment and management of acute stroke	353	Overview of medical care in adults with diabetes mellitus	138	Trimethoprim-sulfamethoxazole (co-trimoxazole): drug information	151	Clinical manifestations and diagnosis of acute pancreatitis	38
4	Overview of the therapy of heart failure due to systolic dysfunction	348	Serologic diagnosis of hepatitis B virus infection	133	Treatment regimens for Helicobacter pylori	143	Shock in adults: types, presentation and diagnostic approach	35
5	Overview of hypertension in adults	347	Treatment and prevention of typhoid fever	127	Tetanus	133	Chronic otitis media, cholesteatoma and mastoiditis in adults	35