Table 1

Epidemiological parameters used in the calculation of DALYs lost secondary to neonatal sepsis in sub-Saharan Africa for the year 2014

Epidemiological parameter	Value	Source	Population
Life expectancy	57	World Bank36	Sub-Saharan Africa
Crude birth rate	37*	World Bank36	Sub-Saharan Africa
Infant mortality	77†	World Bank36	Sub-Saharan Africa
Population	961.5 million	World Bank36	Sub-Saharan Africa
NMR	29†	World Bank36	Sub-Saharan Africa
% NMR attributable to NS	17%–29%	UN IGCME37	Sub-Saharan Africa
Case fatality rate for NS	50%	WHO 20053 38	Sub-Saharan Africa
Incidence of PIH	3–5†	Warf et al 7	Ugandan infants
Risk of cerebral palsy secondary to NS	3.2%–16.3%‡	Consensus from the literature§	International meta-analyses among low birthweight infants in low-income and middle-income countries
Risk of total neurodevelopmental impairment secondary to NS	26.4%–47.4%§	Consensus from the literature§	International meta-analyses among low birthweight infants in low-income and middle-income countries

*Value per 1000 persons.
†Value per 1000 live births.
‡Range gives 95% CI reported in the literature.
§See further discussion in online supplementary materials.
DALY, daily-adjusted life year; NMR, neonatal mortality rate; NS, neonatal sepsis; PIH, postinfectious hydrocephalus; UN IGCME, United Nations Inter-agency Group for Child Mortality Estimation.